A USDA investigation is underway into South Carolina's Alpha Genesis Incorporated after 43 monkeys escaped from its facility.

A South Carolina mother is demanding accountability after her 4-year-old son was left on a school bus and handed to a stranger in a shocking breach of safety protocols.

A South Carolina Republican wants to reintroduce a bill that would make abortions punishable by death.

The owner of a South Carolina pet hospital was allegedly shot "multiple times" in the back by his veterinarian wife just weeks after he filed for separation.

The classmates of a teen bullied her into committing suicide, but after she survived, they then took secret photos of her in a coma to mock her on social media.

A South Carolina mother is suing Mattel after she claims a link misprint took her daughter to a hardcore porn site instead of the movie's website.

George Garner, the late Mayor of the town of McColl, South Carolina, was allegedly connected to an active South Carolina Law Enforcement Division (SLED) investigation, officials say.

The South Carolina biomedical lab is again being criticized for killing up to 20 monkeys after a diesel heater inside the facility malfunctioned sometime Friday night, PETA whistleblowers alleged.

Rep. Nancy Mace (R-SC) has escalated her campaign against transgender rights with a bill to mandate bathroom use on all federal properties.

Three hours north of where a troop of monkeys escaped a lab earlier this month, two female emus, Thelma and Louise, are on the loose in South Carolina.

Authorities are working to capture dozens of monkeys that have escaped from a South Carolina biomedical primate research facility.

A shocking video showed an irate Trump supporter putting his hands on a poll site manager after she asked him to remove his MAGA hat, the latest in a string of attacks on election workers.

South Carolina plans to erect its first-ever statue dedicated to an African American Civil War hero after years of debate.

Charles Dean was killed when a 70-foot red oak tree crashed into his second-floor apartment.

After decades on death row, Richard Moore faces a choice between electrocution or a firing squad, but the former prison chief says he doesn't deserve to die.

A South Carolina man has been charged with killing his wife and his roommates have been charged with helping him move her body weeks after she was reported missing, according to law enforcement.

The couple's grandson John Savage said it was "God's plan" to have them pass together rather than letting one live without the other.

The volunteer said he "absolutely" thinks the fire chief that grounded him put lives at risk.

The photo drew heavy criticism online. The local branch of the NAACP expressed its "profound disappointment."

Cardoso was named as the Most Outstanding Player of the 2024 NCAA Women's Tournament; the third South Carolina player to receive the award

After Iowa and New Hampshire as the first states with election contests, Democrats gear up for South Carolina

A man reportedly fell to his death after he tried to do a handstand on the 15th-floor balcony of a hotel.

A massive search and rescue operation is underway to find survivors following the onslaught of Hurricane Ian.

A man out on bail has been accused of breaking into his former girlfriend's home before proceeding to dump the ashes of her deceased child into the trash in South Carolina on Saturday, Sept. 3.

An 88-year-old Sun City Hilton Head community resident has been confirmed dead after reportedly being violently attacked by a 9-foot alligator after accidentally falling into a pond while gardening in South Carolina.

A man has been reported dead after being attacked and dragged into a retention pond by an alligator near Myrtle Beach, South Carolina on Friday, June 24. 

A foster father in South Carolina was sentenced to 20 years in prison on Thursday for aiding and abetting in the abuse of a 3-year-old which led to her death.

A senior citizen from South Carolina was found dead on Saturday in an apparent heart attack, with his body found next to a hole that he was digging to hide his wife's body.

Richard Bernard Moore's planned April 29 firing squad execution has been halted by South Carolina court.

A South Carolina death row inmate is scheduled for execution on April 29 after being convicted in the 1999 killing of a convenience store clerk.