Rep. Nancy Mace (R-SC) has escalated her campaign against transgender rights with a bill to mandate bathroom use on all federal properties.

Three hours north of where a troop of monkeys escaped a lab earlier this month, two female emus, Thelma and Louise, are on the loose in South Carolina.

Authorities are working to capture dozens of monkeys that have escaped from a South Carolina biomedical primate research facility.

A shocking video showed an irate Trump supporter putting his hands on a poll site manager after she asked him to remove his MAGA hat, the latest in a string of attacks on election workers.

South Carolina plans to erect its first-ever statue dedicated to an African American Civil War hero after years of debate.

Charles Dean was killed when a 70-foot red oak tree crashed into his second-floor apartment.

After decades on death row, Richard Moore faces a choice between electrocution or a firing squad, but the former prison chief says he doesn't deserve to die.

A South Carolina man has been charged with killing his wife and his roommates have been charged with helping him move her body weeks after she was reported missing, according to law enforcement.

The couple's grandson John Savage said it was "God's plan" to have them pass together rather than letting one live without the other.

The volunteer said he "absolutely" thinks the fire chief that grounded him put lives at risk.

The photo drew heavy criticism online. The local branch of the NAACP expressed its "profound disappointment."

Cardoso was named as the Most Outstanding Player of the 2024 NCAA Women's Tournament; the third South Carolina player to receive the award

After Iowa and New Hampshire as the first states with election contests, Democrats gear up for South Carolina

A man reportedly fell to his death after he tried to do a handstand on the 15th-floor balcony of a hotel.

A massive search and rescue operation is underway to find survivors following the onslaught of Hurricane Ian.

A man out on bail has been accused of breaking into his former girlfriend's home before proceeding to dump the ashes of her deceased child into the trash in South Carolina on Saturday, Sept. 3.

An 88-year-old Sun City Hilton Head community resident has been confirmed dead after reportedly being violently attacked by a 9-foot alligator after accidentally falling into a pond while gardening in South Carolina.

A man has been reported dead after being attacked and dragged into a retention pond by an alligator near Myrtle Beach, South Carolina on Friday, June 24. 

A foster father in South Carolina was sentenced to 20 years in prison on Thursday for aiding and abetting in the abuse of a 3-year-old which led to her death.

A senior citizen from South Carolina was found dead on Saturday in an apparent heart attack, with his body found next to a hole that he was digging to hide his wife's body.

Richard Bernard Moore's planned April 29 firing squad execution has been halted by South Carolina court.

A South Carolina death row inmate is scheduled for execution on April 29 after being convicted in the 1999 killing of a convenience store clerk.

Kyleen Waltman, the woman who was mauled by three dogs before being rescued, awakened on Monday to find herself armless, causing distress for the victim before doctors were able to sedate her.

TikTok mother of two Patricia Grooms was murdered on Friday in South Carolina after her body was found in her truck filled up with gunshot wounds.

William Looper has been slapped with a life sentence without parole on Thursday after the South Carolina resident pleaded guilty to the murder and sexual abuse of 2-year-old Brantley Smith.

Imhotep Norman from South Carolina has received a 28-year sentence on Tuesday after leaving his infant daughter Xena to die in a burning car while holding a backpack of illegal drugs.

Zachary Hughes, a Julliard-trained pianist, has been arrested on Wednesday for the murder of South Carolina veterinary tech Christina Larain Parcell, who was found dead in her house on Oct. 15.

Lori and Eric Harmon, previously arrested for having sex in a glass gondola in Myrtle Beach, have been arrested yet again for having public sex in an arcade photo booth.

A 9/11 memorial in South Carolina has been vandalized on the evening of Sept. 11 with the word "Taliban" written over it twice in an act of vandalism.

A Hartford man will serve at least 15 years in jail after he pleaded guilty on Monday to a federal charge of sexually abusing a minor for nearly three years and filming the appalling ordeal, according to the U.S. Attorney’s office.