Mitch McConnell
Mitch McConnell AFP

Republican Senator Mitch McConnell again was the sole GOP lawmaker to vote against Robert Kennedy Jr. to be the next secretary of Health and Human Services, marking the second time he is the lone party holdout in a confirmation vote for President Donald Trump's nominees for his second term.

On Wednesday he had voted against Tulsi Gabbard being the next director of national intelligence, marking the third time he rejects a nominee. The other one was Pete Hegseth, who was ultimately confirmed as Defense Secretary.

None of McConnell's oppositions were successful, as both Gabbard, Kennedy and Hegseth have now been confirmed in their posts. In Hegseth's case he was one of three Republican holdouts along with Lisa Murkowski and Susan Collins, leading Vice President JD Vance to break the 50-50 tie.

The Republican did help tank the nomination of Matt Gaetz, who had to withdraw from consideration as Attorney General after failing to secure enough votes. At least four Republican senators, including McConnell, were "implacably opposed" to his confirmation, the New York Times revealed back in November.

McConnell has opposed Trump more openly since stepping down as the Republican leader in the Upper House and announcing he won't seek reelection after his term ends. In fact, McConnell has called Trump a "narcissist" and saying he was counting the days until he left office in his first term, according to a biography of his that came out last year.

The remarks are part of "The Price of Power," a book by Mitchel Tackett, the deputy Washington bureau chief of The Associated Press. It includes recorded diaries from McConnell spanning almost 30 years and several interviews with him.

Despite this, as well as Trump's visible animosity toward McConnell, the Senate Minority leader endorsed the former president's candidacy earlier in 2024, saying "it should come as no surprise."

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